About Olfactory receptor 5B12
Olfactory receptor 5B12 (OR5B12) is a protein
from Homo sapiens identified by UniProt accession
Q96R08, 314 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Olfactory receptor 5B12 |
|---|
| UniProt accession | Q96R08 |
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| Gene | OR5B12 |
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| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (31)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.36
- diastolic blood pressure · score 0.33
- pulse pressure measurement · score 0.32
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- cortical surface area measurement · score 0.15
- protein measurement · score 0.13
- birth weight · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96R08-F1 | alphafold | PREDICTED | 89.55 | — |
Amino-acid sequence (314 residues)
MENNTEVTEF ILVGLTDDPE LQIPLFIVFL FIYLITLVGN LGMIELILLD SCLHTPMYFF LSNLSLVDFG YSSAVTPKVM VGFLTGDKFI LYNACATQFF FFVAFITAES FLLASMAYDR YAALCKPLHY TTTMTTNVCA CLAIGSYICG FLNASIHTGN TFRLSFCRSN VVEHFFCDAP PLLTLSCSDN YISEMVIFFV VGFNDLFSIL VILISYLFIF ITIMKMRSPE GRQKAFSTCA SHLTAVSIFY GTGIFMYLRP NSSHFMGTDK MASVFYAIVI PMLNPLVYSL RNKEVKSAFK KTVGKAKASI GFIF
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