About Olfactory receptor 2A7
Olfactory receptor 2A7 (OR2A7) is a protein
from Homo sapiens identified by UniProt accession
Q96R45, 310 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 2A7 |
|---|
| UniProt accession | Q96R45 |
|---|
| Gene | OR2A7 |
|---|
| Organism | Homo sapiens |
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| Length | 310 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- colorectal adenocarcinoma · score 0.04
- non-small cell lung carcinoma · score 0.03
- lung adenocarcinoma · score 0.01
- carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96R45-F1 | alphafold | PREDICTED | 79.27 | — |
Amino-acid sequence (310 residues)
MGDNITSITE FLLLGFPVGP RIQMLLFGLF SLFYVFTLLG NGTILGLISL DSRLHAPMYF FLSHLAVVDI AYACNTVPRM LVNLLHPAKP ISFAGRMMQT FLFSTFAVTE CLLLVVMSYD LYVAICHPLR YLAIMTWRVC ITLAVTSWTT GVLLSLIHLV LLLPLPFCRP QKIYHFFCEI LAVLKLACAD THINENMVLA GAISGLVGPL STIVVSYMCI LCAILQIQSR EVQRKAFCTC FSHLCVIGLF YGTAIIMYVG PRYGNPKEQK KYLLLFHSLF NPMLNPLICS LRNSEVKNTL KRVLGVERAL
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