Proteinase-activated receptor 4 (F2RL3)

About Proteinase-activated receptor 4

Proteinase-activated receptor 4 (F2RL3) is a protein from Homo sapiens identified by UniProt accession Q96RI0, 385 residues long. MolForge cross-references it against 0 known binders and 160 disease associations.

Target properties

Protein name	Proteinase-activated receptor 4
UniProt accession	Q96RI0
Gene	F2RL3
Organism	Homo sapiens
Length	385 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96RI0-F1	alphafold	PREDICTED	80.19	—

Amino-acid sequence (385 residues)

MWGRLLLWPL VLGFSLSGGT QTPSVYDESG STGGGDDSTP SILPAPRGYP GQVCANDSDT LELPDSSRAL LLGWVPTRLV PALYGLVLVV GLPANGLALW VLATQAPRLP STMLLMNLAA ADLLLALALP PRIAYHLRGQ RWPFGEAACR LATAALYGHM YGSVLLLAAV SLDRYLALVH PLRARALRGR RLALGLCMAA WLMAAALALP LTLQRQTFRL ARSDRVLCHD ALPLDAQASH WQPAFTCLAL LGCFLPLLAM LLCYGATLHT LAASGRRYGH ALRLTAVVLA SAVAFFVPSN LLLLLHYSDP SPSAWGNLYG AYVPSLALST LNSCVDPFIY YYVSAEFRDK VRAGLFQRSP GDTVASKASA EGGSRGMGTH SSLLQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards