Trace amine-associated receptor 6 (TAAR6)

About Trace amine-associated receptor 6

Trace amine-associated receptor 6 (TAAR6) is a protein from Homo sapiens identified by UniProt accession Q96RI8, 345 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Trace amine-associated receptor 6
UniProt accession	Q96RI8
Gene	TAAR6
Organism	Homo sapiens
Length	345 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.23
lung adenocarcinoma · score 0.18
cutaneous melanoma · score 0.17
endometrial cancer · score 0.16
esophageal cancer · score 0.13
squamous cell lung carcinoma · score 0.12
breast adenocarcinoma · score 0.10
prostate adenocarcinoma · score 0.10
heel bone mineral density · score 0.05
bone density · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96RI8-F1	alphafold	PREDICTED	90.69	—

Amino-acid sequence (345 residues)

MSSNSSLLVA VQLCYANVNG SCVKIPFSPG SRVILYIVFG FGAVLAVFGN LLVMISILHF KQLHSPTNFL VASLACADFL VGVTVMPFSM VRTVESCWYF GRSFCTFHTC CDVAFCYSSL FHLCFISIDR YIAVTDPLVY PTKFTVSVSG ICISVSWILP LMYSGAVFYT GVYDDGLEEL SDALNCIGGC QTVVNQNWVL TDFLSFFIPT FIMIILYGNI FLVARRQAKK IENTGSKTES SSESYKARVA RRERKAAKTL GVTVVAFMIS WLPYSIDSLI DAFMGFITPA CIYEICCWCA YYNSAMNPLI YALFYPWFRK AIKVIVTGQV LKNSSATMNL FSEHI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards