Small proline-rich protein 2F (SPRR2F)

About Small proline-rich protein 2F

Small proline-rich protein 2F (SPRR2F) is a protein from Homo sapiens identified by UniProt accession Q96RM1, 72 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Small proline-rich protein 2F
UniProt accession	Q96RM1
Gene	SPRR2F
Organism	Homo sapiens
Length	72 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
prostate adenocarcinoma · score 0.21
atopic eczema · score 0.14
monocyte count · score 0.11
urinary bladder cancer · score 0.11
psoriasis · score 0.06
esophageal squamous cell carcinoma · score 0.03
esophageal adenocarcinoma · score 0.03
Barrett's esophagus · score 0.03
non-small cell lung carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96RM1-F1	alphafold	PREDICTED	75.69	—

Amino-acid sequence (72 residues)

MSYQQQQCKQ PCQPPPVCPA PKCPEPCPPP KCPEPCPPSK CPQSCPPQQC QQKCPPVTPS PPCQPKCPPK SK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards