Galactose-3-O-sulfotransferase 4 (GAL3ST4)

About Galactose-3-O-sulfotransferase 4

Galactose-3-O-sulfotransferase 4 (GAL3ST4) is a protein from Homo sapiens identified by UniProt accession Q96RP7, 486 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Galactose-3-O-sulfotransferase 4
UniProt accession	Q96RP7
Gene	GAL3ST4
Organism	Homo sapiens
Length	486 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

age at menarche · score 0.12
forced expiratory volume · score 0.08
diet measurement · score 0.07
mean corpuscular volume · score 0.05
leprosy · score 0.05
cortical thickness · score 0.04
FEV/FVC ratio · score 0.03
neuroimaging measurement · score 0.03
brain measurement · score 0.03
diastolic blood pressure · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96RP7-F1	alphafold	PREDICTED	79.32	—

Amino-acid sequence (486 residues)

MGPLSPARTL RLWGPRSLGV ALGVFMTIGF ALQLLGGPFQ RRLPGLQLRQ PSAPSLRPAL PSCPPRQRLV FLKTHKSGSS SVLSLLHRYG DQHGLRFALP ARYQFGYPKL FQASRVKGYR PQGGGTQLPF HILCHHMRFN LKEVLQVMPS DSFFFSIVRD PAALARSAFS YYKSTSSAFR KSPSLAAFLA NPRGFYRPGA RGDHYARNLL WFDFGLPFPP EKRAKRGNIH PPRDPNPPQL QVLPSGAGPR AQTLNPNALI HPVSTVTDHR SQISSPASFD LGSSSFIQWG LAWLDSVFDL VMVAEYFDES LVLLADALCW GLDDVVGFMH NAQAGHKQGL STVSNSGLTA EDRQLTARAR AWNNLDWALY VHFNRSLWAR IEKYGQGRLQ TAVAELRARR EALAKHCLVG GEASDPKYIT DRRFRPFQFG SAKVLGYILR SGLSPQDQEE CERLATPELQ YKDKLDAKQF PPTVSLPLKT SRPLSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards