About cTAGE family member 2
cTAGE family member 2 (CTAGE1) is a protein
from Homo sapiens identified by UniProt accession
Q96RT6, 745 residues long.
MolForge cross-references it against 0 known binders and
71 disease associations.
Target properties
| Protein name | cTAGE family member 2 |
|---|
| UniProt accession | Q96RT6 |
|---|
| Gene | CTAGE1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 745 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (71)
Diseases linked to this target (Open Targets).
- platelet count · score 0.38
- triglyceride measurement · score 0.38
- forced expiratory volume · score 0.37
- FEV/FVC ratio · score 0.36
- angina pectoris · score 0.36
- coronary artery disease · score 0.35
- vital capacity · score 0.34
- electrocardiography · score 0.33
- pulse pressure measurement · score 0.33
- benign prostatic hyperplasia · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96RT6-F1 | alphafold | PREDICTED | 69.42 | — |
Amino-acid sequence (745 residues)
MRPDSHPYGF PWELVIRAAV AGFFAVLFLW RSFRSVTSRL YVRREKKFAV ALSGLIEEKC KLLEKFSLVQ KEYEGYEVES SLKNASFEKE ATEAQSLEAT CEKLNRFNSE LVHEILCLEK ELKEEKSKHS EQNELMADIS KRIQSLEDES KSLKSQVAEA KMTFKRFQAN EERLEIEIQD AWKENSELQE SQKQLLQEAE VWKEQVSELI KQKRTFEDSK VHAEQVLNDK ENHIKTLTER LLKMKDGVAM LEEDVTDDDN LELEMNSESE DGAYLDNPPK GALKKLIHAA KLNASLKTLE GERNQIYIQL SEVDKTKEEL TEHIKNLQTE QASLQSENTH FESENQKLQQ KLKVMTELYQ ENEMKLYRKL IVEEKCRLEK EEKLSKVDEM ISHATEELET YRKRAKDLKE FEKTIHFYQK KIILHEKKAH DNWSAAWTAE RNLNDLRKEN AHNRQKLTEI EFKIKLLEKD PYGLDVPNTA FGRQHSPYGP SPLGWPSSET RASLYPPTLL EGPLRLSPLL PRGGGRGSRG PGNPPDHQIT KERGESSCDR LTDPHRAPSD AGPLAPPWEQ DYRMMFPPPG QSYPDSALPP QRQDRFYSNC ARLSGPAELR SFNMPSLDKM DGSMPSEMES SRNDTKDNLG NLKVPDSSLP AENEATGPGF VPPPLAPIRG LLFPVDTRGP FIRRGPPFPP PPPGTVFGAS PDYFSPRDVP GPPRAPFAMR NVYLPRGFLP YRPPRPAFFP PAPTF
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