Methyltransferase-like 26 (METTL26)

About Methyltransferase-like 26

Methyltransferase-like 26 (METTL26) is a protein from Homo sapiens identified by UniProt accession Q96S19, 204 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Methyltransferase-like 26
UniProt accession	Q96S19
Gene	METTL26
Organism	Homo sapiens
Length	204 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.03
cystatin C measurement · score 0.02
mean corpuscular hemoglobin · score 0.02
reticulocyte count · score 0.02
myxosarcoma · score 0.02
ulcerative colitis · score 0.01
cancer · score 0.01
neoplasm · score 0.00
type 2 diabetes mellitus · score 0.00
lung adenocarcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96S19-F1	alphafold	PREDICTED	97.63	—

Amino-acid sequence (204 residues)

MLVAAAAERN KDPILHVLRQ YLDPAQRGVR VLEVASGSGQ HAAHFARAFP LAEWQPSDVD QRCLDSIAAT TQAQGLTNVK APLHLDVTWG WEHWGGILPQ SLDLLLCINM AHVSPLRCTE GLFRAAGHLL KPRALLITYG PYAINGKISP QSNVDFDLML RCRNPEWGLR DTALLEDLGK ASGLLLERMV DMPANNKCLI FRKN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards