About Cysteine/serine-rich nuclear protein 1
Cysteine/serine-rich nuclear protein 1 (CSRNP1) is a protein
from Homo sapiens identified by UniProt accession
Q96S65, 589 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Cysteine/serine-rich nuclear protein 1 |
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| UniProt accession | Q96S65 |
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| Gene | CSRNP1 |
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| Organism | Homo sapiens |
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| Length | 589 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (70)
Diseases linked to this target (Open Targets).
- platelet count · score 0.39
- sex hormone-binding globulin measurement · score 0.38
- platelet crit · score 0.32
- apolipoprotein A 1 measurement · score 0.28
- serum gamma-glutamyl transferase measurement · score 0.28
- creatinine measurement · score 0.25
- lymphocyte percentage of leukocytes · score 0.15
- mitochondrial DNA measurement · score 0.12
- non-small cell lung carcinoma · score 0.08
- cognitive decline measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96S65-F1 | alphafold | PREDICTED | 58.34 | — |
Amino-acid sequence (589 residues)
MTGLLKRKFD QLDEDNSSVS SSSSSSGCQS RSCSPSSSVS RAWDSEEEGP WDQMPLPDRD FCGPRSFTPL SILKRARRER PGRVAFDGIT VFYFPRCQGF TSVPSRGGCT LGMALRHSAC RRFSLAEFAQ EQARARHEKL RQRLKEEKLE MLQWKLSAAG VPQAEAGLPP VVDAIDDASV EEDLAVAVAG GRLEEVSFLQ PYPARRRRAL LRASGVRRID REEKRELQAL RQSREDCGCH CDRICDPETC SCSLAGIKCQ MDHTAFPCGC CREGCENPMG RVEFNQARVQ THFIHTLTRL QLEQEAESFR ELEAPAQGSP PSPGEEALVP TFPLAKPPMN NELGDNSCSS DMTDSSTASS SASGTSEAPD CPTHPGLPGP GFQPGVDDDS LARILSFSDS DFGGEEEEEE EGSVGNLDNL SCFHPADIFG TSDPGGLASW THSYSGCSFT SGVLDENANL DASCFLNGGL EGSREGSLPG TSVPPSMDAG RSSSVDLSLS SCDSFELLQA LPDYSLGPHY TSQKVSDSLD NIEAPHFPLP GLSPPGDASS CFLESLMGFS EPAAEALDPF IDSQFEDTVP ASLMEPVPV
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