Hyaluronan and proteoglycan link protein 3 (HAPLN3)

About Hyaluronan and proteoglycan link protein 3

Hyaluronan and proteoglycan link protein 3 (HAPLN3) is a protein from Homo sapiens identified by UniProt accession Q96S86, 360 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

Target properties

Protein name	Hyaluronan and proteoglycan link protein 3
UniProt accession	Q96S86
Gene	HAPLN3
Organism	Homo sapiens
Length	360 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96S86-F1	alphafold	PREDICTED	87.33	—

Amino-acid sequence (360 residues)

MGLLLLVPLL LLPGSYGLPF YNGFYYSNSA NDQNLGNGHG KDLLNGVKLV VETPEETLFT YQGASVILPC RYRYEPALVS PRRVRVKWWK LSENGAPEKD VLVAIGLRHR SFGDYQGRVH LRQDKEHDVS LEIQDLRLED YGRYRCEVID GLEDESGLVE LELRGVVFPY QSPNGRYQFN FHEGQQVCAE QAAVVASFEQ LFRAWEEGLD WCNAGWLQDA TVQYPIMLPR QPCGGPGLAP GVRSYGPRHR RLHRYDVFCF ATALKGRVYY LEHPEKLTLT EAREACQEDD ATIAKVGQLF AAWKFHGLDR CDAGWLADGS VRYPVVHPHP NCGPPEPGVR SFGFPDPQSR LYGVYCYRQH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards