About Phosphatidylethanolamine-binding protein 4
Phosphatidylethanolamine-binding protein 4 (PEBP4) is a protein
from Homo sapiens identified by UniProt accession
Q96S96, 227 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Phosphatidylethanolamine-binding protein 4 |
|---|
| UniProt accession | Q96S96 |
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| Gene | PEBP4 |
|---|
| Organism | Homo sapiens |
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| Length | 227 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.39
- lymphocyte percentage of leukocytes · score 0.33
- diet measurement · score 0.28
- urate measurement · score 0.28
- bone density · score 0.28
- hair color · score 0.15
- aspartate aminotransferase measurement · score 0.11
- hair colour measurement · score 0.11
- sex hormone-binding globulin measurement · score 0.11
- PHF-tau measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96S96-F1 | alphafold | PREDICTED | 85.53 | — |
Amino-acid sequence (227 residues)
MGWTMRLVTA ALLLGLMMVV TGDEDENSPC AHEALLDEDT LFCQGLEVFY PELGNIGCKV VPDCNNYRQK ITSWMEPIVK FPGAVDGATY ILVMVDPDAP SRAEPRQRFW RHWLVTDIKG ADLKKGKIQG QELSAYQAPS PPAHSGFHRY QFFVYLQEGK VISLLPKENK TRGSWKMDRF LNRFHLGEPE ASTQFMTQNY QDSPTLQAPR ERASEPKHKN QAEIAAC
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