Myeloid-associated differentiation marker (MYADM)

About Myeloid-associated differentiation marker

Myeloid-associated differentiation marker (MYADM) is a protein from Homo sapiens identified by UniProt accession Q96S97, 322 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein name	Myeloid-associated differentiation marker
UniProt accession	Q96S97
Gene	MYADM
Organism	Homo sapiens
Length	322 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (72)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
infect · score 0.09
infection · score 0.09
pulmonary arterial hypertension · score 0.07
non-small cell lung carcinoma · score 0.06
neoplasm · score 0.05
tumor necrosis factor ligand superfamily member 14 measurement · score 0.03
Pallister-Hall syndrome · score 0.03
interleukin 18 measurement · score 0.03
pro‐interleukin‐16 measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96S97-F1	alphafold	PREDICTED	85.73	—

Amino-acid sequence (322 residues)

MPVTVTRTTI TTTTTSSSGL GSPMIVGSPR ALTQPLGLLR LLQLVSTCVA FSLVASVGAW TGSMGNWSMF TWCFCFSVTL IILIVELCGL QARFPLSWRN FPITFACYAA LFCLSASIIY PTTYVQFLSH GRSRDHAIAA TFFSCIACVA YATEVAWTRA RPGEITGYMA TVPGLLKVLE TFVACIIFAF ISDPNLYQHQ PALEWCVAVY AICFILAAIA ILLNLGECTN VLPIPFPSFL SGLALLSVLL YATALVLWPL YQFDEKYGGQ PRRSRDVSCS RSHAYYVCAW DRRLAVAILT AINLLAYVAD LVHSAHLVFV KV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards