Serine incorporator 2 (SERINC2)

About Serine incorporator 2

Serine incorporator 2 (SERINC2) is a protein from Homo sapiens identified by UniProt accession Q96SA4, 455 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Serine incorporator 2
UniProt accession	Q96SA4
Gene	SERINC2
Organism	Homo sapiens
Length	455 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96SA4-F1	alphafold	PREDICTED	78.49	—

Amino-acid sequence (455 residues)

MGACLGACSL LSCASCLCGS APCILCSCCP ASRNSTVSRL IFTFFLFLGV LVSIIMLSPG VESQLYKLPW VCEEGAGIPT VLQGHIDCGS LLGYRAVYRM CFATAAFFFF FTLLMLCVSS SRDPRAAIQN GFWFFKFLIL VGLTVGAFYI PDGSFTNIWF YFGVVGSFLF ILIQLVLLID FAHSWNQRWL GKAEECDSRA WYAGLFFFTL LFYLLSIAAV ALMFMYYTEP SGCHEGKVFI SLNLTFCVCV SIAAVLPKVQ DAQPNSGLLQ ASVITLYTMF VTWSALSSIP EQKCNPHLPT QLGNETVVAG PEGYETQWWD APSIVGLIIF LLCTLFISLR SSDHRQVNSL MQTEECPPML DATQQQQQVA ACEGRAFDNE QDGVTYSYSF FHFCLVLASL HVMMTLTNWY KPGETRKMIS TWTAVWVKIC ASWAGLLLYL WTLVAPLLLR NRDFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards