About Neurabin-2
Neurabin-2 (PPP1R9B) is a protein
from Homo sapiens identified by UniProt accession
Q96SB3, 817 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Neurabin-2 |
|---|
| UniProt accession | Q96SB3 |
|---|
| Gene | PPP1R9B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 817 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- platelet component distribution width · score 0.32
- heel bone mineral density · score 0.30
- cortical surface area measurement · score 0.28
- cup-to-disc ratio measurement · score 0.27
- neuroimaging measurement · score 0.24
- brain volume measurement · score 0.24
- brain measurement · score 0.22
- bone quantitative ultrasound measurement · score 0.21
- autism spectrum disorder · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96SB3-F1 | alphafold | PREDICTED | 62.33 | — |
Amino-acid sequence (817 residues)
MMKTEPRGPG GPLRSASPHR SAYEAGIQAL KPPDAPGPDE APKGAHHKKY GSNVHRIKSM FLQMGTTAGP SGEAGGGAGL AEAPRASERG VRLSLPRASS LNENVDHSAL LKLGTSVSER VSRFDSKPAP SAQPAPPPHP PSRLQETRKL FERSAPAAAG GDKEAAARRL LRQERAGLQD RKLDVVVRFN GSTEALDKLD ADAVSPTVSQ LSAVFEKADS RTGLHRGPGL PRAAGVPQVN SKLVSKRSRV FQPPPPPPPA PSGDAPAEKE RCPAGQQPPQ HRVAPARPPP KPREVRKIKP VEVEESGESE AESAPGEVIQ AEVTVHAALE NGSTVATAAS PAPEEPKAQA APEKEAAAVA PPERGVGNGR APDVAPEEVD ESKKEDFSEA DLVDVSAYSG LGEDSAGSAL EEDDEDDEED GEPPYEPESG CVEIPGLSEE EDPAPSRKIH FSTAPIQVFS TYSNEDYDRR NEDVDPMAAS AEYELEKRVE RLELFPVELE KDSEGLGISI IGMGAGADMG LEKLGIFVKT VTEGGAAHRD GRIQVNDLLV EVDGTSLVGV TQSFAASVLR NTKGRVRFMI GRERPGEQSE VAQLIQQTLE QERWQREMME QRYAQYGEDD EETGEYATDE DEELSPTFPG GEMAIEVFEL AENEDALSPV DMEPEKLVHK FKELQIKHAV TEAEIQQLKR KLQSLEQEKG RWRVEKAQLE QSVEENKERM EKLEGYWGEA QSLCQAVDEH LRETQAQYQA LERKYSKAKR LIKDYQQKEI EFLKKETAQR RVLEESELAR KEEMDKLLDK ISELEGNLQT LRNSNST
Explore Neurabin-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets