About Spermatid perinuclear RNA-binding protein
Spermatid perinuclear RNA-binding protein (STRBP) is a protein
from Homo sapiens identified by UniProt accession
Q96SI9, 672 residues long.
MolForge cross-references it against 0 known binders and
101 disease associations.
Target properties
| Protein name | Spermatid perinuclear RNA-binding protein |
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| UniProt accession | Q96SI9 |
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| Gene | STRBP |
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| Organism | Homo sapiens |
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| Length | 672 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (101)
Diseases linked to this target (Open Targets).
- body height · score 0.28
- lymphocyte count · score 0.25
- birth weight · score 0.20
- serum gamma-glutamyl transferase measurement · score 0.17
- type 2 diabetes mellitus · score 0.13
- aspartate aminotransferase measurement · score 0.12
- protein measurement · score 0.11
- body mass index · score 0.09
- neuroimaging measurement · score 0.06
- azoospermia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96SI9-F1 | alphafold | PREDICTED | 73.02 | — |
Amino-acid sequence (672 residues)
MRSIRSFAND DRHVMVKHST IYPSPEELEA VQNMVSTVEC ALKHVSDWLD ETNKGTKTEG ETEVKKDEAG ENYSKDQGGR TLCGVMRIGL VAKGLLIKDD MDLELVLMCK DKPTETLLNT VKDNLPIQIQ KLTEEKYQVE QCVNEASIII RNTKEPTLTL KVILTSPLIR DELEKKDGEN VSMKDPPDLL DRQKCLNALA SLRHAKWFQA RANGLKSCVI VLRILRDLCN RVPTWAPLKG WPLELICEKS IGTCNRPLGA GEALRRVMEC LASGILLPGG PGLHDPCERD PTDALSYMTI QQKEDITHSA QHALRLSAFG QIYKVLEMDP LPSSKPFQKY SWSVTDKEGA GSSALKRPFE DGLGDDKDPN KKMKRNLRKI LDSKAIDLMN ALMRLNQIRP GLQYKLLSQS GPVHAPVFTM SVDVDGTTYE ASGPSKKTAK LHVAVKVLQA MGYPTGFDAD IECMSSDEKS DNESKNETVS SNSSNNTGNS TTETSSTLEV RTQGPILTAS GKNPVMELNE KRRGLKYELI SETGGSHDKR FVMEVEVDGQ KFRGAGPNKK VAKASAALAA LEKLFSGPNA ANNKKKKIIP QAKGVVNTAV SAAVQAVRGR GRGTLTRGAF VGATAAPGYI APGYGTPYGY STAAPAYGLP KRMVLLPVMK FPTYPVPHYS FF
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