Zinc finger protein 382 (ZNF382)

About Zinc finger protein 382

Zinc finger protein 382 (ZNF382) is a protein from Homo sapiens identified by UniProt accession Q96SR6, 550 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Zinc finger protein 382
UniProt accession	Q96SR6
Gene	ZNF382
Organism	Homo sapiens
Length	550 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

gonorrhea · score 0.08
esophageal squamous cell carcinoma · score 0.08
acute myeloid leukemia · score 0.07
neoplasm · score 0.07
mean corpuscular volume · score 0.04
stomach neoplasm · score 0.02
pancreatic neoplasm · score 0.02
hepatocellular carcinoma · score 0.01
carcinoma · score 0.01
Sepsis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96SR6-F1	alphafold	PREDICTED	62.72	—

Amino-acid sequence (550 residues)

MPLQGSVSFK DVTVDFTQEE WQQLDPAQKA LYRDVMLENY CHFVSVGFHM AKPDMIRKLE QGEELWTQRI FPSYSYLEED GKTEDVLVKF KEYQDRHSRP LIFINHKKLI KERSNIYGKT FTLGKNRISK TILCEYKPDG KVLKNISELV IRNISPIKEK FGDSTGWEKS LLNTKHEKIH PAVNLHKQTE RVLSGKQELI QHQKVQAPEQ PFDHNECEKS FLMKGMLFTH TRAHRGERTF EYNKDGIAFI EKSSLSVHPS NLMEKKPSAY NKYGKFLCRK PVFIMPQRPQ TEEKPFHCPY CGNNFRRKSY LIEHQRIHTG EKPYVCNQCG KAFRQKTALT LHEKTHIEGK PFICIDCGKS FRQKATLTRH HKTHTGEKAY ECPQCGSAFR KKSYLIDHQR THTGEKPYQC NECGKAFIQK TTLTVHQRTH TGEKPYICNE CGKSFCQKTT LTLHQRIHTG EKPYICNECG KSFRQKAILT VHHRIHTGEK SNGCPQCGKA FSRKSNLIRH QKTHTGEKPY ECKQCGKFFS CKSNLIVHQK THKVETTGIQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards