About Integrator complex subunit 14
Integrator complex subunit 14 (INTS14) is a protein
from Homo sapiens identified by UniProt accession
Q96SY0, 518 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Integrator complex subunit 14 |
|---|
| UniProt accession | Q96SY0 |
|---|
| Gene | INTS14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 518 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.29
- mean corpuscular hemoglobin concentration · score 0.18
- mean corpuscular volume · score 0.18
- mean corpuscular hemoglobin · score 0.13
- blood protein measurement · score 0.10
- erythrocyte count · score 0.09
- reticulocyte count · score 0.08
- heel bone mineral density · score 0.08
- testosterone measurement · score 0.07
- eosinophil count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96SY0-F1 | alphafold | PREDICTED | 86.19 | — |
Amino-acid sequence (518 residues)
MPTVVVMDVS LSMTRPVSIE GSEEYQRKHL AAHGLTMLFE HMATNYKLEF TALVVFSSLW ELMVPFTRDY NTLQEALSNM DDYDKTCLES ALVGVCNIVQ QEWGGAIPCQ VVLVTDGCLG IGRGSLRHSL ATQNQRSESN RFPLPFPFPS KLYIMCMANL EELQSTDSLE CLERLIDLNN GEGQIFTIDG PLCLKNVQSM FGKLIDLAYT PFHAVLKCGH LTADVQVFPR PEPFVVDEEI DPIPKVINTD LEIVGFIDIA DISSPPVLSR HLVLPIALNK EGDEVGTGIT DDNEDENSAN QIAGKIPNFC VLLHGSLKVE GMVAIVQLGP EWHGMLYSQA DSKKKSNLMM SLFEPGPEPL PWLGKMAQLG PISDAKENPY GEDDNKSPFP LQPKNKRSYA QNVTVWIKPS GLQTDVQKIL RNARKLPEKT QTFYKELNRL RKAALAFGFL DLLKGVADML ERECTLLPET AHPDAAFQLT HAAQQLKLAS TGTSEYAAYD QNITPLHTDF SGSSTERI
Explore Integrator complex subunit 14 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets