About Zinc finger and SCAN domain-containing protein 10
Zinc finger and SCAN domain-containing protein 10 (ZSCAN10) is a protein
from Homo sapiens identified by UniProt accession
Q96SZ4, 780 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 10 |
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| UniProt accession | Q96SZ4 |
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| Gene | ZSCAN10 |
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| Organism | Homo sapiens |
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| Length | 780 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (60)
Diseases linked to this target (Open Targets).
- Sensorineural hearing impairment · score 0.43
- Global developmental delay · score 0.43
- sensorineural hearing loss · score 0.43
- sex interaction measurement · score 0.23
- forced expiratory volume · score 0.23
- body height · score 0.20
- mean corpuscular hemoglobin concentration · score 0.12
- grey matter volume measurement · score 0.12
- retinitis pigmentosa · score 0.11
- age-related macular degeneration · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96SZ4-F1 | alphafold | PREDICTED | 65.27 | — |
Amino-acid sequence (780 residues)
MLGESVPAAV EQEQLGEVKL EEEEAVSPED PRRPESRLRP EVAHQLFRCF QYQEDMGPRA SLSRLRELCG HWLRPALHTK KQILELLVLE QFLSVLPPHL LGRLQGQPLR DGEEVVLLLE GIHREPSHAG PLDFSCNAGK SCPRADVTLE EKGCASQVPS HSPKKELPAE EPSVLGPSDE PPRPQPRAAQ PAEPGQWRLP PSSKQPLSPG PQKTFQALQE SSPQGPSPWP EESSRDQELA AVLECLTFED VPENKAWPAH PLGFGSRTPD KEEFKQEEPK GAAWPTPILA ESQADSPGVP GEPCAQSLGR GAAASGPGED GSLLGSSEIL EVKVAEGVPE PNPELQFICA DCGVSFPQLS RLKAHQLRSH PAGRSFLCLC CGKSFGRSSI LKLHMRTHTD ERPHACHLCG HRFRQSSHLS KHLLTHSSEP AFLCAECGRG FQRRASLVQH LLAHAQDQKP PCAPESKAEA PPLTDVLCSH CGQSFQRRSS LKRHLRIHAR DKDRRSSEGS GSRRRDSDRR PFVCSDCGKA FRRSEHLVAH RRVHTGERPF SCQACGRSFT QSSQLVSHQR VHTGEKPYAC PQCGKRFVRR ASLARHLLTH GGPRPHHCTQ CGKSFGQTQD LARHQRSHTG EKPCRCSECG EGFSQSAHLA RHQRIHTGEK PHACDTCGHR FRNSSNLARH RRSHTGERPY SCQTCGRSFR RNAHLRRHLA THAEPGQEQA EPPQECVECG KSFSRSCNLL RHLLVHTGAR PYSCTQCGRS FSRNSHLLRH LRTHARETLY
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