About MAP7 domain-containing protein 2
MAP7 domain-containing protein 2 (MAP7D2) is a protein
from Homo sapiens identified by UniProt accession
Q96T17, 732 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | MAP7 domain-containing protein 2 |
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| UniProt accession | Q96T17 |
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| Gene | MAP7D2 |
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| Organism | Homo sapiens |
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| Length | 732 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (35)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.06
- central nervous system cancer · score 0.04
- ependymoma · score 0.03
- non-small cell lung carcinoma · score 0.03
- astrocytoma · score 0.03
- Abnormality of refraction · score 0.03
- refractive error · score 0.03
- glioblastoma multiforme · score 0.02
- lung carcinoma · score 0.02
- atypical teratoid rhabdoid tumor · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96T17-F1 | alphafold | PREDICTED | 62.26 | — |
Amino-acid sequence (732 residues)
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK SDERQRLAKE RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE QRQREDQKRA AVEEKRKQKL REEEERLEAM MRRSLERTQQ LELKKKYSWG APLAIGPGGH DACDKLSTST MSLPKPTEPP MNKRLSSSTV AISYSPDRVF HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV GKEALSGGEA SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ AAGPQGEEAL EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA AKILAEKRRQ ARLQKEQEEQ ERLEKEEQDR LEREELKRKA EEERLRLEEE ARKQEEERKR QEEEKKKQEG EEKRKAGEEA KRKAEEELLL KEKQEQEKQE KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER KKRIDEIMKR TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS PVSKEELISI PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK RSSENLSLDD CNKNLIEGFN SPGQETPLNT FC
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