Mitochondrial inner membrane protease subunit 2 (IMMP2L)

Homo sapiens — UniProt Q96T52

Gene: IMMP2LHomo sapiensSwissProt reviewed

About Mitochondrial inner membrane protease subunit 2

Mitochondrial inner membrane protease subunit 2 (IMMP2L) is a protein from Homo sapiens identified by UniProt accession Q96T52, 175 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.

Target properties

Protein nameMitochondrial inner membrane protease subunit 2
UniProt accessionQ96T52
GeneIMMP2L
OrganismHomo sapiens
Length175 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (178)

Diseases linked to this target (Open Targets).

  • schizophrenia · score 0.48
  • Tourette syndrome · score 0.46
  • attention deficit hyperactivity disorder · score 0.41
  • autism spectrum disorder · score 0.40
  • anorexia nervosa · score 0.38
  • smoking status measurement · score 0.35
  • bipolar disorder · score 0.34
  • obsessive-compulsive disorder · score 0.34
  • unipolar depression · score 0.34
  • smoking behaviour measurement · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96T52-F1alphafoldPREDICTED87.88—

Amino-acid sequence (175 residues)

MAQSQGWVKR YIKAFCKGFF VAVPVAVTFL DRVACVARVE GASMQPSLNP GGSQSSDVVL LNHWKVRNFE VHRGDIVSLV SPKNPEQKII KRVIALEGDI VRTIGHKNRY VKVPRGHIWV EGDHHGHSFD SNSFGPVSLG LLHAHATHIL WPPERWQKLE SVLPPERLPV QREEE

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Quick facts

UniProtQ96T52
GeneIMMP2L
OrganismHomo sapiens
Length175
Binders0
Diseases178
View on UniProt