About Mitochondrial inner membrane protease subunit 2
Mitochondrial inner membrane protease subunit 2 (IMMP2L) is a protein
from Homo sapiens identified by UniProt accession
Q96T52, 175 residues long.
MolForge cross-references it against 0 known binders and
178 disease associations.
Target properties
| Protein name | Mitochondrial inner membrane protease subunit 2 |
| UniProt accession | Q96T52 |
| Gene | IMMP2L |
| Organism | Homo sapiens |
| Length | 175 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (178)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.48
- Tourette syndrome · score 0.46
- attention deficit hyperactivity disorder · score 0.41
- autism spectrum disorder · score 0.40
- anorexia nervosa · score 0.38
- smoking status measurement · score 0.35
- bipolar disorder · score 0.34
- obsessive-compulsive disorder · score 0.34
- unipolar depression · score 0.34
- smoking behaviour measurement · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96T52-F1 | alphafold | PREDICTED | 87.88 | — |
Amino-acid sequence (175 residues)
MAQSQGWVKR YIKAFCKGFF VAVPVAVTFL DRVACVARVE GASMQPSLNP GGSQSSDVVL LNHWKVRNFE VHRGDIVSLV SPKNPEQKII KRVIALEGDI VRTIGHKNRY VKVPRGHIWV EGDHHGHSFD SNSFGPVSLG LLHAHATHIL WPPERWQKLE SVLPPERLPV QREEE
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