Potassium channel subfamily K member 16 (KCNK16)

About Potassium channel subfamily K member 16

Potassium channel subfamily K member 16 (KCNK16) is a protein from Homo sapiens identified by UniProt accession Q96T55, 309 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Potassium channel subfamily K member 16
UniProt accession	Q96T55
Gene	KCNK16
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.34
urate measurement · score 0.26
fasting blood glucose measurement · score 0.25
lung adenocarcinoma · score 0.23
serum albumin measurement · score 0.23
breast adenocarcinoma · score 0.22
cutaneous melanoma · score 0.16
low density lipoprotein cholesterol measurement · score 0.10
HbA1c measurement · score 0.09
refractive error measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96T55-F1	alphafold	PREDICTED	81.34	—

Amino-acid sequence (309 residues)

MPSAGLCSCW GGRVLPLLLA YVCYLLLGAT IFQLLERQAE AQSRDQFQLE KLRFLENYTC LDQWAMEQFV QVIMEAWVKG VNPKGNSTNP SNWDFGSSFF FAGTVVTTIG YGNLAPSTEA GQVFCVFYAL LGIPLNVIFL NHLGTGLRAH LAAIERWEDR PRRSQVLQVL GLALFLTLGT LVILIFPPMV FSHVEGWSFS EGFYFAFITL STIGFGDYVV GTDPSKHYIS VYRSLAAIWI LLGLAWLALI LPLGPLLLHR CCQLWLLSLR QGCGAKAAPG RRPRRGSTAA RGVQVTPQDF PISKKGLGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards