About CMT1A duplicated region transcript 15 protein
CMT1A duplicated region transcript 15 protein (CDRT15) is a protein
from Homo sapiens identified by UniProt accession
Q96T59, 188 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | CMT1A duplicated region transcript 15 protein |
|---|
| UniProt accession | Q96T59 |
|---|
| Gene | CDRT15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 188 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- refractive error · score 0.27
- Myopia · score 0.25
- age at onset · score 0.25
- Abnormality of refraction · score 0.19
- central corneal thickness · score 0.18
- corneal endothelial cell measurement · score 0.14
- corneal topography · score 0.13
- heel bone mineral density · score 0.10
- adolescent idiopathic scoliosis · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96T59-F1 | alphafold | PREDICTED | 51.68 | — |
Amino-acid sequence (188 residues)
MFSCCFPTSR GCCFRNGGSE SLFRRCRRRL IPHPRRLSPV VIRRIQVPQD SLGQALAGQA TPEIPLGLQL HTVLVQEIQE LIEAQTLAPG PCAEVRALPA PAAEPEPAWE EAPPERALEL EGAPAKDQTN EELPEITEVP ESIKRRLGRR VPAATPAPRG NLLLQAWMRV HSWASRLFAP NVLPGTGP
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