Regulator of microtubule dynamics protein 3 (RMDN3)

About Regulator of microtubule dynamics protein 3

Regulator of microtubule dynamics protein 3 (RMDN3) is a protein from Homo sapiens identified by UniProt accession Q96TC7, 470 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Regulator of microtubule dynamics protein 3
UniProt accession	Q96TC7
Gene	RMDN3
Organism	Homo sapiens
Length	470 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
mean corpuscular volume · score 0.21
Red cell distribution width · score 0.14
mean corpuscular hemoglobin concentration · score 0.13
sex hormone-binding globulin measurement · score 0.13
prostate carcinoma · score 0.12
mean corpuscular hemoglobin · score 0.11
waist-hip ratio · score 0.11
type 2 diabetes mellitus · score 0.09
mathematical ability · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96TC7-F1	alphafold	PREDICTED	72.22	—

Amino-acid sequence (470 residues)

MSRLGALGGA RAGLGLLLGT AAGLGFLCLL YSQRWKRTQR HGRSQSLPNS LDYTQTSDPG RHVMLLRAVP GGAGDASVLP SLPREGQEKV LDRLDFVLTS LVALRREVEE LRSSLRGLAG EIVGEVRCHM EENQRVARRR RFPFVRERSD STGSSSVYFT ASSGATFTDA ESEGGYTTAN AESDNERDSD KESEDGEDEV SCETVKMGRK DSLDLEEEAA SGASSALEAG GSSGLEDVLP LLQQADELHR GDEQGKREGF QLLLNNKLVY GSRQDFLWRL ARAYSDMCEL TEEVSEKKSY ALDGKEEAEA ALEKGDESAD CHLWYAVLCG QLAEHESIQR RIQSGFSFKE HVDKAIALQP ENPMAHFLLG RWCYQVSHLS WLEKKTATAL LESPLSATVE DALQSFLKAE ELQPGFSKAG RVYISKCYRE LGKNSEARWW MKLALELPDV TKEDLAIQKD LEELEVILRD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards