Amelogenin, X isoform (AMELX)

About Amelogenin, X isoform

Amelogenin, X isoform (AMELX) is a protein from Homo sapiens identified by UniProt accession Q99217, 191 residues long. MolForge cross-references it against 0 known binders and 408 disease associations.

Target properties

Protein name	Amelogenin, X isoform
UniProt accession	Q99217
Gene	AMELX
Organism	Homo sapiens
Length	191 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99217-F1	alphafold	PREDICTED	59.59	—

Amino-acid sequence (191 residues)

MGTWILFACL LGAAFAMPLP PHPGHPGYIN FSYEVLTPLK WYQSIRPPYP SYGYEPMGGW LHHQIIPVLS QQHPPTHTLQ PHHHIPVVPA QQPVIPQQPM MPVPGQHSMT PIQHHQPNLP PPAQQPYQPQ PVQPQPHQPM QPQPPVHPMQ PLPPQPPLPP MFPMQPLPPM LPDLTLEAWP STDKTKREEV D

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards