Amelogenin, Y isoform (AMELY)

About Amelogenin, Y isoform

Amelogenin, Y isoform (AMELY) is a protein from Homo sapiens identified by UniProt accession Q99218, 206 residues long. MolForge cross-references it against 0 known binders and 325 disease associations.

Target properties

Protein name	Amelogenin, Y isoform
UniProt accession	Q99218
Gene	AMELY
Organism	Homo sapiens
Length	206 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99218-F1	alphafold	PREDICTED	57.32	—

Amino-acid sequence (206 residues)

MGTWILFACL VGAAFAMPLP PHPGHPGYIN FSYENSHSQA INVDRIALVL TPLKWYQSMI RPPYSSYGYE PMGGWLHHQI IPVVSQQHPL THTLQSHHHI PVVPAQQPRV RQQALMPVPG QQSMTPTQHH QPNLPLPAQQ PFQPQPVQPQ PHQPMQPQPP VQPMQPLLPQ PPLPPMFPLR PLPPILPDLH LEAWPATDKT KQEEVD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards