Tubulin-folding cofactor B (TBCB)

About Tubulin-folding cofactor B

Tubulin-folding cofactor B (TBCB) is a protein from Homo sapiens identified by UniProt accession Q99426, 244 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Tubulin-folding cofactor B
UniProt accession	Q99426
Gene	TBCB
Organism	Homo sapiens
Length	244 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99426-F1	alphafold	PREDICTED	92.44	—

Amino-acid sequence (244 residues)

MEVTGVSAPT VTVFISSSLN TFRSEKRYSR SLTIAEFKCK LELLVGSPAS CMELELYGVD DKFYSKLDQE DALLGSYPVD DGCRIHVIDH SGARLGEYED VSRVEKYTIS QEAYDQRQDT VRSFLKRSKL GRYNEEERAQ QEAEAAQRLA EEKAQASSIP VGSRCEVRAA GQSPRRGTVM YVGLTDFKPG YWIGVRYDEP LGKNDGSVNG KRYFECQAKY GAFVKPAVVT VGDFPEEDYG LDEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards