Proteasome subunit beta type-7 (PSMB7)

About Proteasome subunit beta type-7

Proteasome subunit beta type-7 (PSMB7) is a protein from Homo sapiens identified by UniProt accession Q99436, 277 residues long. MolForge cross-references it against 0 known binders and 140 disease associations.

Target properties

Protein name	Proteasome subunit beta type-7
UniProt accession	Q99436
Gene	PSMB7
Organism	Homo sapiens
Length	277 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99436-F1	alphafold	PREDICTED	90.39	—

Amino-acid sequence (277 residues)

MAAVSVYAPP VGGFSFDNCR RNAVLEADFA KRGYKLPKVR KTGTTIAGVV YKDGIVLGAD TRATEGMVVA DKNCSKIHFI SPNIYCCGAG TAADTDMTTQ LISSNLELHS LSTGRLPRVV TANRMLKQML FRYQGYIGAA LVLGGVDVTG PHLYSIYPHG STDKLPYVTM GSGSLAAMAV FEDKFRPDME EEEAKNLVSE AIAAGIFNDL GSGSNIDLCV ISKNKLDFLR PYTVPNKKGT RLGRYRCEKG TTAVLTEKIT PLEIEVLEET VQTMDTS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards