Glycosyl-phosphatidylinositol-anchored molecule-like protein (GML)

About Glycosyl-phosphatidylinositol-anchored molecule-like protein

Glycosyl-phosphatidylinositol-anchored molecule-like protein (GML) is a protein from Homo sapiens identified by UniProt accession Q99445, 158 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Glycosyl-phosphatidylinositol-anchored molecule-like protein
UniProt accession	Q99445
Gene	GML
Organism	Homo sapiens
Length	158 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99445-F1	alphafold	PREDICTED	76.31	—

Amino-acid sequence (158 residues)

MLLFALLLAM ELPLVAASAT MRAQWTYSLR CHDCAVINDF NCPNIRVCPY HIRRCMTISI RINSRELLVY KNCTNNCTFV YAAEQPPEAP GKIFKTNSFY WVCCCNSMVC NAGGPTNLER DMLPDEVTEE ELPEGTVRLG VSKLLLSFAS IIVSNILP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards