About Stromal cell-derived factor 2
Stromal cell-derived factor 2 (SDF2) is a protein
from Homo sapiens identified by UniProt accession
Q99470, 211 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Stromal cell-derived factor 2 |
|---|
| UniProt accession | Q99470 |
|---|
| Gene | SDF2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- lean body mass · score 0.16
- whole body water mass · score 0.15
- base metabolic rate measurement · score 0.13
- anthropometric measurement · score 0.13
- body weights and measures · score 0.13
- insomnia measurement · score 0.05
- urate measurement · score 0.04
- reticulocyte count · score 0.03
- mean corpuscular volume · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99470-F1 | alphafold | PREDICTED | 90.02 | — |
Amino-acid sequence (211 residues)
MAVVPLLLLG GLWSAVGASS LGVVTCGSVV KLLNTRHNVR LHSHDVRYGS GSGQQSVTGV TSVDDSNSYW RIRGKSATVC ERGTPIKCGQ PIRLTHVNTG RNLHSHHFTS PLSGNQEVSA FGEEGEGDYL DDWTVLCNGP YWVRDGEVRF KHSSTEVLLS VTGEQYGRPI SGQKEVHGMA QPSQNNYWKA MEGIFMKPSE LLKAEAHHAE L
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