Histone H4-like protein type G (H4C7)

About Histone H4-like protein type G

Histone H4-like protein type G (H4C7) is a protein from Homo sapiens identified by UniProt accession Q99525, 98 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Histone H4-like protein type G
UniProt accession	Q99525
Gene	H4C7
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

serum iron measurement · score 0.08
worry measurement · score 0.03
drug use measurement · score 0.03
parental genotype effect measurement · score 0.03
birth weight · score 0.03
BMI-adjusted waist circumference · score 0.03
Red cell distribution width · score 0.03
mean platelet volume · score 0.02
myxedema · score 0.02
schizophrenia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99525-F1	alphafold	PREDICTED	87.01	—

Amino-acid sequence (98 residues)

MSVRGKAGKG LGKGGAKCHR KVLSDNIQGI TKCTIRRLAR HGGVKRILGL IYEETRRVFK VFLENVIWYA VTNTEHAKRK TVTAMAVVYV LKRQGRTL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards