Protein FEV (FEV)

Homo sapiens — UniProt Q99581

Gene: FEVHomo sapiensSwissProt reviewed

About Protein FEV

Protein FEV (FEV) is a protein from Homo sapiens identified by UniProt accession Q99581, 238 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein nameProtein FEV
UniProt accessionQ99581
GeneFEV
OrganismHomo sapiens
Length238 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (103)

Diseases linked to this target (Open Targets).

  • sudden infant death syndrome · score 0.37
  • Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor · score 0.37
  • Olfactory Neuroblastoma · score 0.37
  • malignant soft tissue neoplasm · score 0.37
  • Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone · score 0.37
  • neurodegenerative disease · score 0.33
  • colorectal adenocarcinoma · score 0.28
  • prostate adenocarcinoma · score 0.28
  • hepatocellular carcinoma · score 0.28
  • gastric adenocarcinoma · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q99581-F1alphafoldPREDICTED65.68—

Amino-acid sequence (238 residues)

MRQSGASQPL LINMYLPDPV GDGLFKDGKN PSWGPLSPAV QKGSGQIQLW QFLLELLADR ANAGCIAWEG GHGEFKLTDP DEVARRWGER KSKPNMNYDK LSRALRYYYD KNIMSKVHGK RYAYRFDFQG LAQACQPPPA HAHAAAAAAA AAAAAQDGAL YKLPAGLAPL PFPGLSKLNL MAASAGVAPA GFSYWPGPGP AATAAAATAA LYPSPSLQPP PGPFGAVAAA SHLGGHYH

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Quick facts

UniProtQ99581
GeneFEV
OrganismHomo sapiens
Length238
Binders0
Diseases103
View on UniProt