About Protein FEV
Protein FEV (FEV) is a protein
from Homo sapiens identified by UniProt accession
Q99581, 238 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Protein FEV |
| UniProt accession | Q99581 |
| Gene | FEV |
| Organism | Homo sapiens |
| Length | 238 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (103)
Diseases linked to this target (Open Targets).
- sudden infant death syndrome · score 0.37
- Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor · score 0.37
- Olfactory Neuroblastoma · score 0.37
- malignant soft tissue neoplasm · score 0.37
- Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone · score 0.37
- neurodegenerative disease · score 0.33
- colorectal adenocarcinoma · score 0.28
- prostate adenocarcinoma · score 0.28
- hepatocellular carcinoma · score 0.28
- gastric adenocarcinoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q99581-F1 | alphafold | PREDICTED | 65.68 | — |
Amino-acid sequence (238 residues)
MRQSGASQPL LINMYLPDPV GDGLFKDGKN PSWGPLSPAV QKGSGQIQLW QFLLELLADR ANAGCIAWEG GHGEFKLTDP DEVARRWGER KSKPNMNYDK LSRALRYYYD KNIMSKVHGK RYAYRFDFQG LAQACQPPPA HAHAAAAAAA AAAAAQDGAL YKLPAGLAPL PFPGLSKLNL MAASAGVAPA GFSYWPGPGP AATAAAATAA LYPSPSLQPP PGPFGAVAAA SHLGGHYH
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