About Max-binding protein MNT
Max-binding protein MNT (MNT) is a protein
from Homo sapiens identified by UniProt accession
Q99583, 582 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Max-binding protein MNT |
|---|
| UniProt accession | Q99583 |
|---|
| Gene | MNT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 582 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.30
- neurodegenerative disease · score 0.28
- mathematical ability · score 0.27
- diet measurement · score 0.26
- mean corpuscular volume · score 0.25
- alcohol consumption measurement · score 0.22
- insomnia measurement · score 0.22
- erythrocyte count · score 0.22
- appendicular lean mass · score 0.19
- mean corpuscular hemoglobin · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99583-F1 | alphafold | PREDICTED | 59.34 | — |
Amino-acid sequence (582 residues)
MSIETLLEAA RFLEWQAQQQ QRAREEQERL RLEQEREQEQ KKANSLARLA HTLPVEEPRM EAPPLPLSPP APPPAPPPPL ATPAPLTVIP IPVVTNSPQP LPPPPPLPAA AQPLPLAPRQ PALVGAPGLS IKEPAPLPSR PQVPTPAPLL PDSKATIPPN GSPKPLQPLP TPVLTIAPHP GVQPQLAPQQ PPPPTLGTLK LAPAEEVKSS EQKKRPGGIG TREVHNKLEK NRRAHLKECF ETLKRNIPNV DDKKTSNLSV LRTALRYIQS LKRKEKEYEH EMERLAREKI ATQQRLAELK HELSQWMDVL EIDRVLRQTG QPEDDQASTS TASEGEDNID EDMEEDRAGL GPPKLSHRPQ PELLKSTLPP PSTTPAPLPP HPHPHPHSVA LPPAHLPVQQ QQPQQKTPLP APPPPPAAPA QTLVPAPAHL VATAGGGSTV IAHTATTHAS VIQTVNHVLQ GPGGKHIAHI APSAPSPAVQ LAPATPPIGH ITVHPATLNH VAHLGSQLPL YPQPVAVSHI AHTLSHQQVN GTAGLGPPAT VMAKPAVGAQ VVHHPQLVGQ TVLNPVTMVT MPSFPVSTLK LA
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