Mitochondrial import inner membrane translocase…

About Mitochondrial import inner membrane translocase subunit Tim17-A

Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) is a protein from Homo sapiens identified by UniProt accession Q99595, 171 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Mitochondrial import inner membrane translocase subunit Tim17-A
UniProt accession	Q99595
Gene	TIMM17A
Organism	Homo sapiens
Length	171 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.24
lung adenocarcinoma · score 0.07
metabolite measurement · score 0.07
lung carcinoma · score 0.03
neoplasm · score 0.02
breast cancer · score 0.02
cancer · score 0.01
breast carcinoma · score 0.01
lymph node metastatic carcinoma · score 0.01
hypertension · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99595-F1	alphafold	PREDICTED	81.24	—

Amino-acid sequence (171 residues)

MEEYAREPCP WRIVDDCGGA FTMGTIGGGI FQAIKGFRNS PVGVNHRLRG SLTAIKTRAP QLGGSFAVWG GLFSMIDCSM VQVRGKEDPW NSITSGALTG AILAARNGPV AMVGSAAMGG ILLALIEGAG ILLTRFASAQ FPNGPQFAED PSQLPSTQLP SSPFGDYRQY Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A)