T cell receptor gamma variable 9 (TRGV9)

About T cell receptor gamma variable 9

T cell receptor gamma variable 9 (TRGV9) is a protein from Homo sapiens identified by UniProt accession Q99603, 122 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	T cell receptor gamma variable 9
UniProt accession	Q99603
Gene	TRGV9
Organism	Homo sapiens
Length	122 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.05
infection · score 0.03
infect · score 0.03
viral disease · score 0.03
Rheumatoid arthritis · score 0.02
neoplasm · score 0.01
Pallister-Hall syndrome · score 0.01
acute myeloid leukemia · score 0.01
COVID-19 · score 0.01
endolymphatic hydrops · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99603-F1	alphafold	PREDICTED	89.71	—

Amino-acid sequence (122 residues)

MLSLLHTSTL AVLGALCVYG AGHLEQPQIS STKTLSKTAR LECVVSGITI SATSVYWYRE RPGEVIQFLV SISYDGTVRK ESGIPSGKFE VDRIPETSTS TLTIHNVEKQ DIATYYCALW EV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards