About Krueppel-like factor 6
Krueppel-like factor 6 (KLF6) is a protein
from Homo sapiens identified by UniProt accession
Q99612, 283 residues long.
MolForge cross-references it against 0 known binders and
330 disease associations.
Target properties
| Protein name | Krueppel-like factor 6 |
|---|
| UniProt accession | Q99612 |
|---|
| Gene | KLF6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 283 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (330)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.61
- monocyte count · score 0.49
- heel bone mineral density · score 0.47
- mean corpuscular volume · score 0.45
- gastric cancer · score 0.45
- gastric carcinoma · score 0.44
- prostate adenocarcinoma · score 0.44
- erythrocyte count · score 0.42
- mean reticulocyte volume · score 0.42
- body height · score 0.40
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99612-F1 | alphafold | PREDICTED | 57.95 | — |
Amino-acid sequence (283 residues)
MDVLPMCSIF QELQIVHETG YFSALPSLEE YWQQTCLELE RYLQSEPCYV SASEIKFDSQ EDLWTKIILA REKKEESELK ISSSPPEDTL ISPSFCYNLE TNSLNSDVSS ESSDSSEELS PTAKFTSDPI GEVLVSSGKL SSSVTSTPPS SPELSREPSQ LWGCVPGELP SPGKVRSGTS GKPGDKGNGD ASPDGRRRVH RCHFNGCRKV YTKSSHLKAH QRTHTGEKPY RCSWEGCEWR FARSDELTRH FRKHTGAKPF KCSHCDRCFS RSDHLALHMK RHL
Explore Krueppel-like factor 6 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets