C-C motif chemokine 13 (CCL13)

About C-C motif chemokine 13

C-C motif chemokine 13 (CCL13) is a protein from Homo sapiens identified by UniProt accession Q99616, 98 residues long. MolForge cross-references it against 0 known binders and 296 disease associations.

Target properties

Protein name	C-C motif chemokine 13
UniProt accession	Q99616
Gene	CCL13
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (296)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.31
glioblastoma multiforme · score 0.26
protein measurement · score 0.22
neurodegenerative disease · score 0.22
breast adenocarcinoma · score 0.17
Rheumatoid arthritis · score 0.09
major depressive disorder · score 0.08
chronic obstructive pulmonary disease · score 0.08
post-traumatic stress disorder · score 0.08
oral squamous cell carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99616-F1	alphafold	PREDICTED	84.84	—

Amino-acid sequence (98 residues)

MKVSAVLLCL LLMTAAFNPQ GLAQPDALNV PSTCCFTFSS KKISLQRLKS YVITTSRCPQ KAVIFRTKLG KEICADPKEK WVQNYMKHLG RKAHTLKT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards