Protein C10 (C12orf57)

About Protein C10

Protein C10 (C12orf57) is a protein from Homo sapiens identified by UniProt accession Q99622, 126 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Protein C10
UniProt accession	Q99622
Gene	C12orf57
Organism	Homo sapiens
Length	126 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

temtamy syndrome · score 0.81
Aicardi-Goutieres syndrome 9 · score 0.51
Global developmental delay · score 0.40
neurodegenerative disease · score 0.34
Intellectual disability · score 0.34
hydronephrosis · score 0.33
vesicoureteral reflux · score 0.33
attention deficit hyperactivity disorder · score 0.33
Seizure · score 0.26
Abnormal corpus callosum morphology · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99622-F1	alphafold	PREDICTED	80.03	—

Amino-acid sequence (126 residues)

MASASTQPAA LSAEQAKVVL AEVIQAFSAP ENAVRMDEAR DNACNDMGKM LQFVLPVATQ IQQEVIKAYG FSCDGEGVLK FARLVKSYEA QDPEIASLSG KLKALFLPPM TLPPHGPAAG GSVAAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards