Cell cycle checkpoint control protein RAD9A (RAD9A)

About Cell cycle checkpoint control protein RAD9A

Cell cycle checkpoint control protein RAD9A (RAD9A) is a protein from Homo sapiens identified by UniProt accession Q99638, 391 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.

Target properties

Protein name	Cell cycle checkpoint control protein RAD9A
UniProt accession	Q99638
Gene	RAD9A
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (87)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.28
lung adenocarcinoma · score 0.28
endometrial cancer · score 0.27
neurodegenerative disease · score 0.23
gastric adenocarcinoma · score 0.17
mean corpuscular hemoglobin · score 0.12
mean corpuscular volume · score 0.12
red blood cell density measurement · score 0.08
body weight · score 0.08
insulin like growth factor measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99638-F1	alphafold	PREDICTED	75.99	—

Amino-acid sequence (391 residues)

MKCLVTGGNV KVLGKAVHSL SRIGDELYLE PLEDGLSLRT VNSSRSAYAC FLFAPLFFQQ YQAATPGQDL LRCKILMKSF LSVFRSLAML EKTVEKCCIS LNGRSSRLVV QLHCKFGVRK THNLSFQDCE SLQAVFDPAS CPHMLRAPAR VLGEAVLPFS PALAEVTLGI GRGRRVILRS YHEEEADSTA KAMVTEMCLG EEDFQQLQAQ EGVAITFCLK EFRGLLSFAE SANLNLSIHF DAPGRPAIFT IKDSLLDGHF VLATLSDTDS HSQDLGSPER HQPVPQLQAH STPHPDDFAN DDIDSYMIAM ETTIGNEGSR VLPSISLSPG PQPPKSPGPH SEEEDEAEPS TVPGTPPPKK FRSLFFGSIL APVRSPQGPS PVLAEDSEGE G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards