Cell growth regulator with EF hand domain protein 1 (CGREF1)

About Cell growth regulator with EF hand domain protein 1

Cell growth regulator with EF hand domain protein 1 (CGREF1) is a protein from Homo sapiens identified by UniProt accession Q99674, 318 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Cell growth regulator with EF hand domain protein 1
UniProt accession	Q99674
Gene	CGREF1
Organism	Homo sapiens
Length	318 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99674-F1	alphafold	PREDICTED	62.05	—

Amino-acid sequence (318 residues)

MLPLTMTVLI LLLLPTGQAA PKDGVTRPDS EVQHQLLPNP FQPGQEQLGL LQSYLKGLGR TEVQLEHLSR EQVLLYLFAL HDYDQSGQLD GLELLSMLTA ALAPGAANSP TTNPVILIVD KVLETQDLNG DGLMTPAELI NFPGVALRHV EPGEPLAPSP QEPQAVGRQS LLAKSPLRQE TQEAPGPREE AKGQVEARRE SLDPVQEPGG QAEADGDVPG PRGEAEGQAE AKGDAPGPRG EAGGQAEAEG DAPGPRGEAG GQAEAEGDAP GPRGEAGGQA EARENGEEAK ELPGETLESK NTQNDFEVHI VQVENDEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards