About Homeobox protein Meis3
Homeobox protein Meis3 (MEIS3) is a protein
from Homo sapiens identified by UniProt accession
Q99687, 375 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Homeobox protein Meis3 |
|---|
| UniProt accession | Q99687 |
|---|
| Gene | MEIS3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 375 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- anti-chlamydia trachomatis antibody measurement · score 0.03
- monocyte count · score 0.02
- esophageal squamous cell carcinoma · score 0.01
- Klinefelter's syndrome · score 0.01
- endometrial carcinoma · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99687-F1 | alphafold | PREDICTED | 64.90 | — |
Amino-acid sequence (375 residues)
MARRYDELPH YPGIVDGPAA LASFPETVPA VPGPYGPHRP PQPLPPGLDS DGLKREKDEI YGHPLFPLLA LVFEKCELAT CSPRDGAGAG LGTPPGGDVC SSDSFNEDIA AFAKQVRSER PLFSSNPELD NLMIQAIQVL RFHLLELEKV HDLCDNFCHR YITCLKGKMP IDLVIEDRDG GCREDFEDYP ASCPSLPDQN NMWIRDHEDS GSVHLGTPGP SSGGLASQSG DNSSDQGDGL DTSVASPSSG GEDEDLDQER RRNKKRGIFP KVATNIMRAW LFQHLSHPYP SEEQKKQLAQ DTGLTILQVN NWFINARRRI VQPMIDQSNR TGQGAAFSPE GQPIGGYTET QPHVAVRPPG SVGMSLNLEG EWHYL
Explore Homeobox protein Meis3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets