Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB)

About Heterogeneous nuclear ribonucleoprotein A/B

Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) is a protein from Homo sapiens identified by UniProt accession Q99729, 332 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	Heterogeneous nuclear ribonucleoprotein A/B
UniProt accession	Q99729
Gene	HNRNPAB
Organism	Homo sapiens
Length	332 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99729-F1	alphafold	PREDICTED	64.45	—

Amino-acid sequence (332 residues)

MSEAGEEQPM ETTGATENGH EAVPEASRGR GWTGAAAGAG GATAAPPSGN QNGAEGDQIN ASKNEEDAGK MFVGGLSWDT SKKDLKDYFT KFGEVVDCTI KMDPNTGRSR GFGFILFKDA ASVEKVLDQK EHRLDGRVID PKKAMAMKKD PVKKIFVGGL NPESPTEEKI REYFGEFGEI EAIELPMDPK LNKRRGFVFI TFKEEEPVKK VLEKKFHTVS GSKCEIKVAQ PKEVYQQQQY GSGGRGNRNR GNRGSGGGGG GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards