C-C motif chemokine 19 (CCL19)

About C-C motif chemokine 19

C-C motif chemokine 19 (CCL19) is a protein from Homo sapiens identified by UniProt accession Q99731, 98 residues long. MolForge cross-references it against 0 known binders and 364 disease associations.

Target properties

Protein name	C-C motif chemokine 19
UniProt accession	Q99731
Gene	CCL19
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (364)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.26
blood protein measurement · score 0.12
neoplasm · score 0.11
cancer · score 0.09
chronic rhinosinusitis with nasal polyps · score 0.09
hepatocellular carcinoma · score 0.08
breast cancer · score 0.08
chronic hepatitis B virus infection · score 0.08
Rheumatoid arthritis · score 0.07
acute lymphoblastic leukemia · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99731-F1	alphafold	PREDICTED	83.20	—

Amino-acid sequence (98 residues)

MALLLALSLL VLWTSPAPTL SGTNDAEDCC LSVTQKPIPG YIVRNFHYLL IKDGCRVPAV VFTTLRGRQL CAPPDQPWVE RIIQRLQRTS AKMKRRSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards