Microsomal glutathione S-transferase 2 (MGST2)

About Microsomal glutathione S-transferase 2

Microsomal glutathione S-transferase 2 (MGST2) is a protein from Homo sapiens identified by UniProt accession Q99735, 147 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.

Target properties

Protein name	Microsomal glutathione S-transferase 2
UniProt accession	Q99735
Gene	MGST2
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99735-F1	alphafold	PREDICTED	94.58	—

Amino-acid sequence (147 residues)

MAGNSILLAA VSILSACQQS YFALQVGKAR LKYKVTPPAV TGSPEFERVF RAQQNCVEFY PIFIITLWMA GWYFNQVFAT CLGLVYIYGR HLYFWGYSEA AKKRITGFRL SLGILALLTL LGALGIANSF LDEYLDLNIA KKLRRQF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards