About MyoD family inhibitor
MyoD family inhibitor (MDFI) is a protein
from Homo sapiens identified by UniProt accession
Q99750, 246 residues long.
MolForge cross-references it against 0 known binders and
104 disease associations.
Target properties
| Protein name | MyoD family inhibitor |
|---|
| UniProt accession | Q99750 |
|---|
| Gene | MDFI |
|---|
| Organism | Homo sapiens |
|---|
| Length | 246 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (104)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.32
- chronotype measurement · score 0.14
- mean corpuscular volume · score 0.10
- self reported educational attainment · score 0.08
- lung adenocarcinoma · score 0.07
- heel bone mineral density · score 0.05
- autosomal recessive spondylocostal dysostosis · score 0.05
- non-small cell lung carcinoma · score 0.05
- autosomal dominant spondylocostal dysostosis · score 0.05
- spondylometaphyseal dysplasia, A4 type · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99750-F1 | alphafold | PREDICTED | 50.65 | — |
Amino-acid sequence (246 residues)
MYQVSGQRPS GCDAPYGAPS AAPGPAQTLS LLPGLEVVTG STHPAEAAPE EGSLEEAATP MPQGNGPGIP QGLDSTDLDV PTEAVTCQPQ GNPLGCTPLL PNDSGHPSEL GGTRRAGNGA LGGPKAHRKL QTHPSLASQG SKKSKSSSKS TTSQIPLQAQ EDCCVHCILS CLFCEFLTLC NIVLDCATCG SCSSEDSCLC CCCCGSGECA DCDLPCDLDC GILDACCESA DCLEICMECC GLCFSS
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