NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial (COQ7)

Homo sapiens — UniProt Q99807

Gene: COQ7Homo sapiensSwissProt reviewed

About NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial

NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial (COQ7) is a protein from Homo sapiens identified by UniProt accession Q99807, 217 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein nameNADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial
UniProt accessionQ99807
GeneCOQ7
OrganismHomo sapiens
Length217 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q99807-F1alphafoldPREDICTED86.91—

Amino-acid sequence (217 residues)

MSCAGAAAAP RLWRLRPGAR RSLSAYGRRT SVRFRSSGMT LDNISRAAVD RIIRVDHAGE YGANRIYAGQ MAVLGRTSVG PVIQKMWDQE KDHLKKFNEL MVTFRVRPTV LMPLWNVLGF ALGAGTALLG KEGAMACTVA VEESIAHHYN NQIRTLMEED PEKYEELLQL IKKFRDEELE HHDIGLDHDA ELAPAYAVLK SIIQAGCRVA IYLSERL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

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Quick facts

UniProtQ99807
GeneCOQ7
OrganismHomo sapiens
Length217
Binders0
Diseases41
View on UniProt