Paired mesoderm homeobox protein 2 (PRRX2)

About Paired mesoderm homeobox protein 2

Paired mesoderm homeobox protein 2 (PRRX2) is a protein from Homo sapiens identified by UniProt accession Q99811, 253 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Paired mesoderm homeobox protein 2
UniProt accession	Q99811
Gene	PRRX2
Organism	Homo sapiens
Length	253 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99811-F1	alphafold	PREDICTED	66.42	—

Amino-acid sequence (253 residues)

MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards