Probable rRNA-processing protein EBP2 (EBNA1BP2)

About Probable rRNA-processing protein EBP2

Probable rRNA-processing protein EBP2 (EBNA1BP2) is a protein from Homo sapiens identified by UniProt accession Q99848, 306 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

Target properties

Protein name	Probable rRNA-processing protein EBP2
UniProt accession	Q99848
Gene	EBNA1BP2
Organism	Homo sapiens
Length	306 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (70)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.24
cystatin C measurement · score 0.15
creatinine measurement · score 0.14
blood phosphate measurement · score 0.14
kidney injury molecule 1 measurement · score 0.12
hemoglobin D disease · score 0.05
dominant beta-thalassemia · score 0.05
hemoglobin H disease · score 0.05
hemoglobin C-beta-thalassemia syndrome · score 0.04
hemoglobin E disease · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99848-F1	alphafold	PREDICTED	75.18	—

Amino-acid sequence (306 residues)

MDTPPLSDSE SESDESLVTD RELQDAFSRG LLKPGLNVVL EGPKKAVNDV NGLKQCLAEF KRDLEWVERL DVTLGPVPEI GGSEAPAPQN KDQKAVDPED DFQREMSFYR QAQAAVLAVL PRLHQLKVPT KRPTDYFAEM AKSDLQMQKI RQKLQTKQAA MERSEKAKQL RALRKYGKKV QTEVLQKRQQ EKAHMMNAIK KYQKGFSDKL DFLEGDQKPL AQRKKAGAKG QQMRKGPSAK RRYKNQKFGF GGKKKGSKWN TRESYDDVSS FRAKTAHGRG LKRPGKKGSN KRPGKRTREK MKNRTH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards