Forkhead box protein B1 (FOXB1)

About Forkhead box protein B1

Forkhead box protein B1 (FOXB1) is a protein from Homo sapiens identified by UniProt accession Q99853, 325 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Forkhead box protein B1
UniProt accession	Q99853
Gene	FOXB1
Organism	Homo sapiens
Length	325 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99853-F1	alphafold	PREDICTED	64.89	—

Amino-acid sequence (325 residues)

MPRPGRNTYS DQKPPYSYIS LTAMAIQSSP EKMLPLSEIY KFIMDRFPYY RENTQRWQNS LRHNLSFNDC FIKIPRRPDQ PGKGSFWALH PSCGDMFENG SFLRRRKRFK VLKSDHLAPS KPADAAQYLQ QQAKLRLSAL AASGTHLPQM PAAAYNLGGV AQPSGFKHPF AIENIIAREY KMPGGLAFSA MQPVPAAYPL PNQLTTMGSS LGTGWPHVYG SAGMIDSATP ISMASGDYSA YGVPLKPLCH AAGQTLPAIP VPIKPTPAAV PALPALPAPI PTLLSNSPPS LSPTSSQTAT SQSSPATPSE TLTSPASALH SVAVH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards