Histone H2A type 1-J (H2AC14)

Homo sapiens — UniProt Q99878

Gene: H2AC14Homo sapiensSwissProt reviewed

About Histone H2A type 1-J

Histone H2A type 1-J (H2AC14) is a protein from Homo sapiens identified by UniProt accession Q99878, 128 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein nameHistone H2A type 1-J
UniProt accessionQ99878
GeneH2AC14
OrganismHomo sapiens
Length128 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q99878-F1alphafoldPREDICTED91.80—

Amino-acid sequence (128 residues)

MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHHKTK

Explore Histone H2A type 1-J with MolForge

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Quick facts

UniProtQ99878
GeneH2AC14
OrganismHomo sapiens
Length128
Binders0
Diseases72
View on UniProt