Histone H2B type 1-M (H2BC14)

Homo sapiens — UniProt Q99879

Gene: H2BC14Homo sapiensSwissProt reviewed

About Histone H2B type 1-M

Histone H2B type 1-M (H2BC14) is a protein from Homo sapiens identified by UniProt accession Q99879, 126 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein nameHistone H2B type 1-M
UniProt accessionQ99879
GeneH2BC14
OrganismHomo sapiens
Length126 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q99879-F1alphafoldPREDICTED87.38—

Amino-acid sequence (126 residues)

MPEPVKSAPV PKKGSKKAIN KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT KYTSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Explore Histone H2B type 1-M with MolForge

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Quick facts

UniProtQ99879
GeneH2BC14
OrganismHomo sapiens
Length126
Binders0
Diseases49
View on UniProt